Tubersol is a prescription solution that is injected just under the skin to test for tuberculosis infection.
TUBERSOL®, a product of Sanofi Pasteur Limited, is in shortage nationwide. This is a prescription solution that is injected just under the skin by a healthcare provider to test for tuberculosis infection. This is impacting healthcare providers using the solution for their testing.
Healthcare - Recommends Approaches
The Centers for Disease Control and Prevention recommends approaches for healthcare providers to address the shortage.
Learn more about the current shortage.
Franklin County Public Health (FCPH) investigated a Legionellosis outbreak associated with the Wesley Ridge Retirement Community, located at 2225 Taylor Park in Reynoldsburg, in July and August 2013. The Centers for Disease Control and Prevention (CDC) and the Ohio Department of Health (ODH) assisted with the investigation. There were a total of 39 confirmed cases. The age range was 63-99 years of age. There were six deaths.
FCPH, CDC and ODH worked together to complete case interviews and investigations as well as patient chart review. The data was compiled and reviewed to see if a common exposure source could be determined. Water tests have confirmed legionella was present in both the potable water system and a cooling tower. The Wesley Ridge Retirement Community followed all recommendations to limit additional exposure to their residents, employees and visitors. They hired a contractor to test their environmental systems and completed remediation.
For additional information on this Legionellosis outbreak, contact FCPH at (614) 525-3097 or IDRS at (614) 525-8888.
As Ohio’s 2013 agricultural fair season kicks off, the Ohio Departments of Health (ODH) and Agriculture (ODA) are reminding Ohioans to practice good hygiene when visiting livestock exhibits as the H3N2 variant virus (H3N2v) makes another comeback this year. This virus is also known as the flu virus from swine exposure.
Last year, 309 cases in 12 states (including Ohio) were part of an outbreak caused by H3N2v. Most of these infections were associated with prolonged exposure to pigs at agricultural fairs.
Influenza viruses such as H3N2 and its variants are not unusual in swine and can be directly transmitted from swine to people and from people to swine in the same way that all viruses can be transmitted between people. When humans are in close proximity to live infected swine, such as in barns and livestock exhibits at fairs, movement of these viruses can occur back and forth between humans and animals. Influenza viruses cannot be transmitted by eating pork or pork products.
Individuals should always wash hands with soap and water before and after petting or touching any animal. Never eat, drink, or put anything in your mouth in animal areas. Older adults, pregnant women, young children, and people with weakened immune systems should be extra careful around animals.
Those who have direct, routine contact with swine, such as working in swine barns or showing swine at fairs, and have experienced cough or influenza-like illness should contact their health care provider or local health department. Symptoms include cough, sore throat, fever, body aches, and possibly other symptoms, such as nausea, vomiting or diarrhea.
CDC Health Alert Network (HAN) Advisory
Feb 14 - New CRE Warrant Additional Action by Healthcare Providers
CDC Morbidity and Mortality Weekly Report (MMWR)
Mar 05 - Vital Signs: Carbapenem-Resistant Enterobacteriaceae
Feb 15 - Notes from the Field: Hospital Outbreak of Carbapenem-Resistant Klebsiella pneumoniae Producting New Delhi Metallo-Beta-Lactamase
Mar 05 - CDC Vital Signs Press Release Graphic: Making Health Care Safer
CDC is coordinating a multi-state investigation of fungal meningitis among patients who received epidural steroid injections (medication injected into the spine). Several of these patients have had strokes related to the meningitis. Cases have all linked to back injections with steroids distributed by the New England Compounding Center (NECC). The investigation also includes fungal infections associated with injections in a peripheral joint space, such as a knee, shoulder or ankle. Fungal meningitis is not contagious. For additional information on the investigation visit the CDC web site.
A total of four clinics in Ohio were identified to have received one of the recalled lots from the NECC associated with illness. One is from here in Franklin County – the Ortho-Spine Rehab Center in Dublin. That clinic, along with Franklin County Public Health, has contacted the patients who received the recalled epidural and advised them what symptoms to closely watch for.
On October 3, 2012, NECC ceased all production and initiated recall of all methylprednisolone acetate (a steroid medication) and other drug products prepared for injections in and around the spinal cord (known as intrathecal administration). On October 6, NECC announced a recall of all its products. A complete list of all products subject to this recall can be accessed here. Franklin County Public Health, Columbus Public Health and the Ohio Department of Health (ODH) alerted health care providers to inform them of symptoms that could be cause by the tainted drug as well as updated lists of recalled products.
All health care providers have been asked to follow-up with patients who received any injectable products from NECC since May 2012. The products on the expanded list have not been linked to any illnesses, FDA is providing the information out of an abundance of caution. The Centers for Disease Control and Prevention (CDC) has provided states with a list from the Food and Drug Administration (FDA) of all facilities that purchased NECC products during that time frame. ODH is making the list of the 64 Ohio facilities available online to aid in the outreach to patients. The list includes any provider who bought a NECC product since May 21, 2012, even topical products, which FDA has indicated are low- or no-risk products.
For details on cases in Ohio visit the Ohio Department of Health web site.
Fungal Meningitis related to this recall is considered a Class A Disease and must be reported within 24 hours.
CDC Health Alert Network (HAN) Alerts
Dec 3 - Update: Additional Contamination Identified in Medical Products from New England Compounding Center
Nov 20 - Update: Multistate Outbreak of Fungal Meningitis and Other Infections Associated with Contaminated Steroid Medication
Nov 1 - Contamination Identified in Additional Medical Products from New England Compounding Center
Nov 1 - Voluntary Recall of All Ameridose Medical Products
Oct 23 - Issuance of Guidance on Management of Asymptomatic Patients Who Received Epidural or Paraspinal Injections with Contaminated Steroid Products
Oct 17 - Update: Multistate Outbreak of Fungal Meningitis and Joint Infections Associated with Contaminated Steroid Medications
Oct 8 - Multistate Outbreak of Meningitis and Stroke Associated with Potentially Contaminated Steroid Medication
Oct 4 - Meningitis and Stroke Associated with Potentially Contaminated Product
CPH & FCPH Update
Oct 7 - Ohio Emergency Medicine Care Providers Memo
Ohio Department of Health News Releases
Oct 16 - Ohio Department of Health News Release
Oct 11 - Ohio Department of Health News Release
Oct 8 - Ohio Department of Health News Release
Oct 6 - Ohio Department of Health News Release
Oct 5 - Ohio Department of Health News Release
CDC Recommendations for Clinicians
Because recommendations are evolving daily, please visit the CDC web site for the most current guidelines.
Oct 6 - Treatment Guidance for Fungal Meningitis
Oct 6 - Diagnostic Testing & Specimen Submission Guidance
Oct 6 - Case Definition
As of September 28, 307 cases of variant Influenza A ("H3N2v") associated with swine exposure have been confirmed by the Centers for Disease Control and Prevention (CDC). To see the breakdown of the 10 states with cases, visit the CDC web site.
As of the end of September there were 107 confirmed cases in Ohio. Those with confirmed cases are between the ages six months and 61 years. Most ill individuals have recovered on their own or were treated and released after a short stay in the hospital. One death in Madison County has been associated with H3N2v. Individuals most likely became ill with the flu virus after exposure to swine. Some limited human-to-human passage of the virus has been confirmed. To see the breakdown of the counties with cases visit the Ohio Department of Health web site.
Because of the number of cases in Ohio, as well as confirmed H3N2v activity in other states, Columbus Public Health and Franklin County Public Health are conducting enhanced surveillance for outbreaks and unusual cases of influenza-like illnesses (ILI). ILI is defined as fever ≥ 100° F and cough and/or sore throat in the absence of a known cause other than influenza.
Who is at Risk
People in close proximity to live infected swine, such as in barns and livestock exhibits at fairs. Children, pregnant women, elderly, and those with compromised immune systems should be especially careful around swine.
For all persons with ILI that report direct contact with swine, please complete the Novel Virus Infection Confidential Case Report Form. Call (614) 525-8888 to report and fax form to (614) 525-8890.
Lab and Specimen Testing
At this time, Ohio Department of Health Lab will accept specimens for testing in the following situations:
For patients in Franklin County and Columbus who fall under the above situations, please call the Franklin County and Columbus disease reporting line at (614) 525-8888 to report a suspected case and arrange for sample submission.
Ohio Department of Health News Releases
Aug 31 - Ohio Documents First H3N2v-Associated Death
Aug 24 - Ohio Documents 98 Human Cases of Influenza A H3N2v
Aug 14 - H3N2v Update: 54 Cases Confirmed
Aug 10 - County Fair Outreach Underway
Aug 08 - Additional H3N2v Cases Confirmed in Ohio
Aug 06 - Additional H3N2v Cases in Ohio Confirmed by CDC
Aug 03 - State Officials Continue Flu Surveillance and Prevention
Aug 02 - Health Officials Confirm Flu Virus Strain from Butler County Fair
Aug 01 - Health Officials Investigating Flu Illnesses from Butler County Fair
Aug 3 - CDC Increase in Influenza A H3N2v Virus Infections in Three U.S. States
Aug 3 - Healthcare Provider Advisory
Aug 3 - Influenza A Novel Virus Infection Confidential Case Report